ANTICANCER PROPERTIES

WHEATGRASS IS EFFECTIVE AGAINST CANCER

There has been an increase of cancer cases and deaths. In addition to high costs or lack of therapeutic interventions, side effects associated with the conventional (usual) treatments of chemotherapy and radiotherapy has added misery to those seeking treatment.Other than immediate access to treatment, PREVENTION! is the best approach in combating cancer.

WHEATGRASS has been proved highly beneficial in CANCER;

  • prevention and
  • management by:-

Reduction of nausea and vomiting,

Reduction of anemia,

Better response to treatment.

continuous therapy without stoppage,

without diminishing efficacy of chemotherapy.

rsz_manual-wheatgrass-juicer

The anticancer properties of wheatgrass is due to:-

  1. chlorophyll of chlorophyllin,
  2. bioflavonoids like apigenin, quercitin and luteolin.
  3. indole compounds, choline and laetrile (amygdalin).
  4. antioxidant enzyme Superoxide dismutase (SOD).
  5. the plant hormone abscisic acid (ABA) or dormin.
  6. high alkalinity (Ph 7.4)

ANTICANCER MECHANISM

Mechanisms by which wheatgrass appears beneficial include:-

  • antioxidant activity preventing oxidative damage to deoxyribonucleic acid (DNA) and lipid peroxidation,
  • stimulation of gap junction communication,
  • effects on cell transformation and differentiation,
  • inhibition of cell proliferation and oncogene expression,
  • effects on immune function and inhibition of endogenous formation of carcinogens.

Wheatgrass intake enhances hemoglobin synthesis as chlorophyll bears a structural analogy to hemoglobin. This results in augmented oxygen supply to all body cells including cancer cells which are highly vulnerable to high oxygen concentration due to the deleterious effects caused by the generation of reactive oxygen species (ROS). The enzyme SOD catalyses the generation of hydrogen peroxide from superoxide radicals, and thus further ads onto this effect. Chlorophyll, like other tetrapyrroles, has the ability to induce mammalian phase 2 proteins that protect cells against oxidants and electrophiles. The capacity of this compound to induce the phase 2 response depends upon its ability or that of its metabolites to react with thiol groups. Its pseudo second-order rate constant is correlated with its potency in inducing the phase 2 enzyme NAD (P)H:quinone oxidoreductase 1 (NQO1) in murine hepatoma cells. One of the most potent inducers was isolated from chlorophyllin, a semisynthetic water-soluble chlorophyll derivative. Although chlorophyll itself is low in inducer potency, it may nevertheless account for some of the disease- protective effects attributed to diets rich in green vegetables like wheatgrass because it occurs in much higher concentrations in these plants.

Another constituent of wheatgrass implicated as an anticancer agent is the plant hormone abscisic acid (ABA) or dormin. This hormone is 40 times more potent 4 hours after cutting the wheatgrass plant. ABA can neutralize the effect of the hormone chorionic gonadotropin and a compound similar to this hormone has been found to be produced by the cancer cells.

A novel anticancer approach utilizes high alkalinity in the cancer chemotherapy. Firstly, an alkaline diet helps to reduce the number of microbes in the diet. This attenuates the incidence of secondary infections to a certain degree in the patient. Secondly, the cancer cells succumb in a highly alkaline environment. As the pH of the wheatgrass juice is around 7.4, it is being considered a viable option under this approach.

Other postulated mechanisms by which wheatgrass juice appears beneficial include antioxidant activity preventing oxidative damage to deoxyribonucleic acid (DNA) and lipid peroxidation, stimulation of gap junction communication, effects on cell transformation and differentiation, inhibition of cell proliferation and oncogene expression, effects on immune function and inhibition of endogenous formation of carcinogens.

CLINICAL APPLICATIONS

The consumption of Wheatgrass during FAC (5–fluorouracil, doxorubicin and cyclophospamide) chemotherapy is attributed to:-

  • reduced myelo-toxicity,
  • dose reduction,
  • continuous therapy without stoppage,
  • reduced need for granulocyte colony stimulating factors (GCSF) support,

without diminishing efficacy of chemotherapy.

Wheat grass juice helps to improve the health status and lifespan of terminally ill cancer patients and hence very valuable in palliative care.

The extract of wheat grass when applied to known chemical mutagens, decreased their cancer causing ability by up to 99 percent, reduce the production of carcinogenic, aromatic hydrocarbon (Benzopyerene) derivative and to inhibit benzopyerene mutagenecity which suggests that wheat grass have cancer preventing property.

The clinical studies conducted on patients of transfusion dependent myelodysplastic syndrome (pre leukemia) have revealed that Wheat Grass Juice is an effective iron chelator and its use in reducing serum ferritin should be encouraged in myelodysplastic syndrome and other diseases where repeated blood transfusion is required.